质子及重离子治疗肿瘤的现状及研究进展

2020年12月13日发(作者：吕作松)
质子及重离子治疗肿瘤的现状及研究进展
王谨;陈明


【期刊名称】《中华放射医学与防护杂志》

【年(卷),期】2016(036)008

【摘要】Protons and heavy ion radiation therapy have proven highly
effective against a wide range of cancers and in recent decades there
have been rapid to the physical characteristics of the
Bragg-peak and superior biological properties,proton and heavy ion
radiation is able to focus its energy on the tumor while minimizing
exposure to surrounding normal tissues and organs,which is expected
help enhance the tumor dose and reduce normal tissue
recent years,many studies have explored the efficacy and safety of
proton and heavy ion radiotherapy on various malignancies,such as
head and neck cancer,lung cancer,esophageal cancer,and liver
results of these studies enable a better understanding of the
characteristics and advantages of proton and heavy ion therapy.%质子和
重离子射线治疗肿瘤,是利用质子和重离子穿过物质形 成Bragg峰的物理特性和
重离子优越的放射生物学特性,将高剂量区调整嵌合在肿瘤上,同时尽量避 开周围
正常组织器官.质子及重离子放疗剂量分布优于光子放疗,这有利于提升肿瘤剂量
和降低 正常组织损伤.近年来,不少研究探索了质子重离子治疗头颈部肿瘤、肺癌、
食管癌、肝癌等肿瘤的有效 性及安全性,而多个对比光子及质子治疗肿瘤的临床
研究也正在进行中.这些研究的结果将有利于更好地 了解质子及重离子治疗的特